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生物信息学

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余智慧

作者: 阅读次数: 日期:2025-12-21

2025年6月毕业于电子科技大学生物医学工程专业获得工学博士学位。2025年11月进入枣庄学院生命科学学院工作。聚焦于植物分子细胞生物学领域,核心围绕栽培小麦的遗传改良展开。针对栽培小麦在抗逆、抗病、优质等方面的育种需求,以染色体工程为核心技术手段,结合分子标记辅助选择、细胞学、生物信息学等方法,系统挖掘黑麦、簇毛麦、偃麦草等小麦族珍稀物种中蕴藏的优异基因资源,将其定向转移至栽培小麦基因组中,为培育高产、优质、多抗的小麦新品种提供理论支撑与材料基础。近年来在《Agronomy》、《Plants-Basel》和《Genome》等期刊发表SCI论文10余篇。

近年来发表的代表性论文:

[1] Yu Zhihui, Wang Hongjin, Xu Yunfang, et al. Characterization of chromosomal rearrangement in new wheat-Thinopyrum intermedium addition lines carrying Thinopyrum-specific grain hardness genes[J]. Agronomy, 2019, 9(1):18.

[2] Yu Zhihui, Wang Hongjin, Yang Ennian, et al. Precise Identification of chromosome constitution and rearrangements in wheat-Thinopyrum intermedium derivatives by ND-FISH and Oligo-FISH painting. Plants (Basel). 2022, 11(16): 2109.

[3] Yu Zhihui, Wang Hongjin, Jiang Wenxi, et al. Karyotyping Dasypyrum breviaristatum chromosomes with multiple oligonucleotide probes reveals the genomic divergence in Dasypyrum. Genome. 2021, 64(8): 789-800.

[4] Wang Hongjin, Yu Zhihui#, Li Bin, et al. Characterization of new wheat-Dasypyrum breviaristatum introgression lines with superior gene(s) for spike length and stripe rust resistance. Cytogenet Genome Res. 2018, 156(2): 117-125.

[5] Yu Zhihui, Wang Hongjin, Li Guangrong, et al. Characterization of new wheat-Thinopyrum intermedium derivative lines with superior genes for stripe rust and powdery mildew resistance. [J]. Plants (Basel), 2024, 13: 2333.

[6] Wang Xiaolu, Yu Zhihui, Wang Hongjin, et al. Characterization, identification and evaluation of wheat-Aegilops sharonensis chromosome derivatives. Front Plant Sci. 2021, 12: 708551.

[7] Li Jianbo, Yu Zhihui, Zhang Ahui, et al. Physical mapping of chromosome 7J and a purple coleoptile gene from Thinopyrum intermedium in the common wheat background. Planta. 2021, 253(1): 22.

[8] Wang Hongjin, Yu Zhihui, Li Guangrong, et al. Diversified chromosome rearrangements detected in a wheat-Dasypyrum breviaristatum substitution line induced by gamma-ray irradiation. Plants (Basel). 2019, 8(6): 175.

[9] Li Guangrong, Zhang Tao, Yu Zhihui, et al. An efficient Oligo-FISH painting system for revealing chromosome rearrangements and polyploidization in Triticeae. Plant J. 2021, 105(4): 978-993.

[10] Lang Tao, Li Guangrong, Yu Zhihui, et al.Genome-wide distribution of novel Ta-3A1 mini-Satellite repeats and its use for chromosome identification in wheat and related species[J]. Agronomy, 2019(2): 60.

[11] Lang Tao, Li Guangrong, Wang Hongjin, Yu Zhihui, et al. Physical location of tandem repeats in the wheat genome and application for chromosome identification. Planta. 2019, 249(3): 663-675.

[12] Wang Hongjin, Zhang Hongjun, Li Bin, Yu Zhihui, et al. Molecular cytogenetic characterization of new wheat-Dasypyrum breviaristatum introgression lines for improving grain quality of wheat. Front Plant Sci. 2018, 9: 365.

[13] Lang Tao, La Shixiao, Li Bin, Yu zhihui, et al. Precise identification of wheat - Thinopyrum intermedium translocation chromosomes carrying resistance to wheat stripe rust in line Z4 and its derived progenies. Genome. 2018, 61(3): 177-185.