Hasan Muhammad （哈桑）

学位：博士

职称：外籍专家老师

E-mail：waqqas.hasan@gmail.com, 2023390085@gzhmu.edu.cn

研究方向：纳米疫苗与核酸药物递送、抗寄生虫免疫调节、肿瘤免疫治疗

Hasan Muhammad Waqqas博士，2022年毕业于南京农业大学分子寄生虫学与免疫学专业，获博士学位。2023年至2026年在广州医科大学从事博士后研究工作，并于2026年8月加入枣庄学院工作。其主要研究方向为纳米生物技术、免疫调节与精准药物递送，重点聚焦于基于纳米颗粒及mRNA平台的抗寄生虫疫苗开发与肿瘤免疫治疗，同时围绕宿主先天免疫调控机制、STING信号通路激活策略及智能核酸药物递送系统开展系统性研究。近年来，以第一作者、共同第一作者及参与作者身份发表SCI论文30余篇，研究成果见于《Advanced Drug Delivery Reviews》《Journal of Nanobiotechnology》《Vaccines》《Frontiers in Immunology》《Chinese Chemical Letters》等国际权威期刊。在寄生虫亚单位疫苗构建、纳米佐剂设计及肿瘤免疫联合治疗等方面积累了较为丰富的科研经验。

近年来发表的代表性论文：

[1] Muhammad Waqqas Hasan, Jiajia Pan, Ningbo Xia, and Wenjie Chen. mRNA based vaccines and therapeutics for parasitic infections: a comprehensive review. Journal of Nanobiotechnology, 2025.

[2] Muhammad Waqqas Hasan, Javaid Ali Gadahi, Muhammad Haseeb, Qiangqiang Wang, Muhammad Ehsan, Shakeel Ahmad Lakho, Ali Haider, Tahir Aleem, Mingmin Lu, Ruofeng Yan, Xiaokai Song, Xiangrui Li, and Lixin Xu. Partial Protection of Goats against Haemonchus contortus Achieved with ADP-Ribosylation Factor 1 Encapsulated in PLGA Nanoparticles. Vaccines, 2024, 12(10).

[3] Muhammad Waqqas Hasan, Muhammad Haseeb, Javaid Ali Gadahi, Muhammad Ehsan, Qiangqiang Wang, Shakeel Ahmed Lakho, Ali Haider, Muhammad Tahir Aleem, Kalibixiati Aimulajiang, Mingmin Lu, Lixin Xu, Xiaokai Song, Xiangrui Li, and Ruofeng Yan. Nanoparticle containing recombinant excretory/secretory-24 protein of Haemonchus contortus enhanced the cellular immune responses in mice. Frontiers in Veterinary Science, 2024, 11.

[4] Muhammad Waqqas Hasan, Muhammad Ehsan, Qiangqiang Wang, Muhammad Haseeb, Shakeel Ahmed Lakho, Ali Haider, Mingmin Lu, Lixin Xu, Xiaokai Song, Ruofeng Yan, and Xiangrui Li. PLGA-Encapsulated Haemonchus contortus Antigen ES-15 Augments Immune Responses in a Murine Model. Vaccines, 2023, 11(12).

[5] Muhammad Waqqas Hasan, Muhammad Haseeb, Muhammad Ehsan, Javaid Ali Gadahi, Qiangqiang Wang, Muhammad Ali Memon, Muhammad Tahir Aleem, Shakeel Ahmed Lakho, Ruo Feng Yan, Li Xin Xu, Xiao Kai Song, and Xiangrui Li. The immunogenic maturation of goat monocyte-derived dendritic cells and upregulation of toll-like receptors by five antigens of Haemonchus contortus in-vitro. Research in Veterinary Science, 2021, 136, 247-258. #

[6] Muhammad Waqqas Hasan, Muhammad Haseeb, Muhammad Ehsan, Javaid Ali Gadahi, Muhammad Ali-ul-Husnain Naqvi, Qiang Qiang Wang, Xinchao Liu, Shakeel Ahmed Lakho, Ruofeng Yan, Lixin Xu, Xiaokai Song, and Xiangrui Li. Nanoparticles (PLGA and Chitosan)-Entrapped ADP-Ribosylation Factor 1 of Haemonchus contortus Enhances the Immune Responses in ICR Mice. Vaccines, 2020, 8, 726.