
2025年12月毕业于南京师范大学细胞生物学专业获得理学博士学位。2026年1月进入枣庄学院生命科学学院工作。主要从事帕金森病相关研究,聚焦蛋白质相分离及淀粉样聚集的分子机制。近五年来以第一作者或共同作者在《Cell Reports》、《Journal of Cell Biology》、《Journal of Biological Chemistry》、《Biomolecules》、《ACS Omega》、《Chembiochem》、《Biochem Biophys Res Commun》等刊物上发表SCI论文7篇。
近年来发表的代表性论文:
[1] Xu, B., He, W., Fan, F., Chen, S., Zhu, M., Hou, Y., Zheng, L., Yu, H., and Liu, Y. (2025). β-synuclein blocks α-synuclein condensate fusion to disrupt the maturation of phase separation. Cell Rep 44, 115761.
[2] Xu, B., Fan, F., Liu, Y., Liu, Y., Zhou, L., and Yu, H. (2023). Distinct effects of familial Parkinson's disease-associated mutations on α-synuclein phase separation and amyloid aggregation. Biomolecules 13, 726.
[3] Xu, B., Huang, S., Liu, Y., Wan, C., Gu, Y., Wang, D., and Yu, H. (2022). Manganese promotes α-synuclein amyloid aggregation through the induction of protein phase transition. J Biol Chem 298, 101469.
[4] Xu, B., Chen, J., and Liu, Y. (2022). Curcumin interacts with α-synuclein condensates to inhibit amyloid aggregation under phase separation. ACS Omega 7, 30281-30290.
[5] Xu, B., Mo, X., Chen, J., Yu, H., and Liu, Y. (2022). Myricetin inhibits α-synuclein amyloid aggregation by delaying the liquid-to-solid phase transition. ChemBioChem 23, e202200216.
[6] Zhu, M., Xu, H., Jin, Y., Kong, X., Xu, B., Liu, Y., and Yu, H. (2024). Synaptotagmin-1 undergoes phase separation to regulate its calcium-sensitive oligomerization. J Cell Biol 223, e202311191.
[7] Huang, S., Xu, B., and Liu, Y. (2022). Calcium promotes α-synuclein liquid-liquid phase separation to accelerate amyloid aggregation. Biochem Biophys Res Commun 603, 13-20.